Treatment Algorithm for Ameloblastoma

نویسندگان

  • Madhumati Singh
  • Anjan Shah
  • Auric Bhattacharya
  • Ragesh Raman
  • Narahari Ranganatha
  • Piyush Prakash
چکیده

Ameloblastoma is the second most common benign odontogenic tumour (Shafer et al. 2006) which constitutes 1-3% of all cysts and tumours of jaw, with locally aggressive behaviour, high recurrence rate, and a malignant potential (Chaine et al. 2009). Various treatment algorithms for ameloblastoma have been reported; however, a universally accepted approach remains unsettled and controversial (Chaine et al. 2009). The treatment algorithm to be chosen depends on size (Escande et al. 2009 and Sampson and Pogrel 1999), anatomical location (Feinberg and Steinberg 1996), histologic variant (Philipsen and Reichart 1998), and anatomical involvement (Jackson et al. 1996). In this paper various such treatment modalities which include enucleation and peripheral osteotomy, partial maxillectomy, segmental resection and reconstruction done with fibula graft, and radical resection and reconstruction done with rib graft and their recurrence rate are reviewed with study of five cases.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Unicystic Ameloblastoma: Differential Diagnosis and Treatment Planning

Unicystic ameloblastoma is a tumor of odontogenic origin. It is not a rare neoplasm and most often the lesion is asympthomatic. However, large lesions may cause painless swelling of the jaws. Here we report a case of unicystic ameloblastoma with pain, swelling of the posterior jaws along with teeth mobility. Samples of incisional biopsy of the lesion and also interaoperative frozen section were...

متن کامل

ارزیابی بیان ایمونوهیستوشیمیایی ماتریکس متالوپروتئیناز ٢ در آملوبلاستومای داخل استخوانی توپر ، یونی سیستیک و محیطی

Background & Aims: Ameloblastoma is a slow growing, locally invasive epithelial odontogenic tumor and high rate of recurrence. Mechanisms involving ameloblastoma invasiveness are poorly understood, and no definitive treatment procedures for individual variants are mentioned in the literature. Matrix metalloproteinases (MMPs) especially MMP-2 causes degradation of the matrix thereby promoting in...

متن کامل

Retrospective study of ameloblastoma: the possibility of conservative treatment.

At our institutions, most cases of the solid or multicystic type were treated as conservatively as possible in order to avoid disadvantages of radical treatment. The aim of present study was to retrospectively analyze the ameloblastoma cases diagnosed at our two institutions, to classify them according to the criteria of the 2005 WHO classification, and to evaluate the possibility of using a co...

متن کامل

Ameloblastoma - A Case Report

This article highlights features of ameloblastoma which could be mistaken for a malignant tumor. Ameloblastoma is usually multilocular but may also present itself as unilocular radiolucency. Ameloblastomas are nototrious for their local invasiveness and their tendency to recur. It shows an aggressive behavior leaving surgical resection as one of the most practical approach towards treatment. Al...

متن کامل

BRAF inhibitor treatment of primary BRAF-mutant ameloblastoma with pathologic assessment of response.

OBJECTIVE Molecular characterization of ameloblastoma has indicated a high frequency of driver mutations in BRAF and SMO. Preclinical data suggest that Food and Drug Administration-approved BRAF-targeted therapies may be immediately relevant for patients with ameloblastoma positive for the BRAF V600E mutation. METHODS A neoadjuvant treatment regime of dabrafenib was given to a patient with re...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2014  شماره 

صفحات  -

تاریخ انتشار 2014